Non-syndromic orofacial clefting (NSOFC) is a group of craniofacial defects, including cleft lip (CL), cleft lip and palate (CLP), and isolated cleft palate (CP), not associated with other syndromes. NSOFC is a common birth defect worldwide, with an estimated global prevalence of 1.47/1000 live births. The etiology of NSOFC is complex, involving genetic and environmental factors, making it challenging to identify exact causal factors. In Saudi Arabia, NSOFC incidence is 1.26/1000 live births, lower than the global prevalence but higher than 2015 data. Consanguineous marriage rates vary, with Riyadh having a prevalence of 60%. Maternal exposure to antipyretics, folic acid, fever, antibiotics, illnesses, paternal waterpipe smoking, stress, x-rays, and chemicals can interact with maternal gene variants, affecting the risk of oral cleft. A multidisciplinary team manages orofacial cleft patients, developing comprehensive treatment plans tailored to each patient. Orthodontic interventions, such as maxillary protraction and surgical approaches, enhance facial harmony, function, and self-confidence. The multidisciplinary approach highlights the impact of orthodontic interventions in improving the well-being of cleft patientsu


Learning Objectives
After this lecture, you will be able to understand the significant role of orthodontists within multidisciplinary teams, and how they contribute to transforming the lives of individuals with craniofacial anomalies.
After this lecture, you will be able to gain insight into the specialized treatment approaches utilized in addressing craniofacial anomalies, along with the associated challenges and remarkable outcomes.
After this lecture, you will be able to gain insight into the specialized treatment approaches utilized in addressing craniofacial anomalies, along with the associated challenges and remarkable outcomes.